Archive for the Systems Biology Articles

ICAT Proteomics Technology Reveals Connection Between Two Cellular Structures

A combination of novel techniques for identifying key proteins and imaging their localization in cells is proving to be powerful method for unraveling possible mechanisms underlying cancerous growth. In the November 19th issue of Molecular Cell, researchers at the Institute for Systems Biology (ISB) report that technology developed at the ISB and applied in a new way to fission yeast, a model organism sharing striking similarity with growth mechanisms in humans, has led to an important new insight that could lead to a better understanding of how cellular growth becomes unregulated during carcinogenesis.

The Molecular Pages of the mesotelencephalic dopamine consortium (DopaNet)

DopaNet (http://www.dopanet.org) is a Systems Biology initiative that aims to investigate precisely and quantitatively all the aspects of neurotransmission in a specific neuronal system.

Completion of Haloarcula marismortui Genome Sequencing Featured in Genome Research

Scientists at the Institute for Systems Biology (ISB) in collaboration with researchers from National Yan Ming University (NYMU) in Taiwan and University of Texas at Austin have fully sequenced the complete genome of Haloarcula marismortui, a microorganism that thrives in the Dead Sea.
Their findings are featured on the cover of this month’s issue of the [...]

Completion of Haloarcula marismortui Genome Sequencing Featured in Genome Research

Scientists at the Institute for Systems Biology (ISB) in collaboration with researchers from National Yan Ming University (NYMU) in Taiwan and University of Texas at Austin have fully sequenced the complete genome of Haloarcula marismortui, a microorganism that thrives in the Dead Sea.
Their findings are featured on the cover of this month’s issue of the journal Genome Research. This highly collaborative study was supported by research grants from multiple funding agencies including the National Science Foundation, U.S. Department of Energy and Department of Defense and the National Science Council of Taiwan and spearheaded by Drs. Nitin S. Baliga, ISB senior scientist and his colleague Victor Wailap Ng (currently at NYMU)also of ISB.