Researchers at Rensselaer Polytechnic Institute have found a new pathway by which cells change their adhesive properties.

Scientists eager to help develop a new generation of pharmaceuticals are studying cellular proteins called transcription factors, which bind to upstream sequences of genes to turn the expression of those genes on or off. Some pharmaceutical companies are also hoping to develop drugs that selectively block the binding of transcription factors as a way to […]

EML Research and the Virginia Bioinformatics Institute (VBI) at Virginia Tech today announced the launch of the COPASI simulation software. COPASI (Complex Pathway Simulator) is a major software package that allows users to model, simulate and analyze biochemical and systems biology networks. COPASI, which supports the Systems Biology Markup Language (SBML)

Scientists at the University of California, San Diego and three other institutions have described for the first time a web of inter-related responses that cells use to avoid becoming diseased or cancerous after being exposed to a powerful chemical mutagen.

In an important step toward accelerating drug discovery, researchers have created computer models of more than 900 cell receptors from a class of proteins known to be important drug targets. The models, which are now freely available to noncommercial users, promise to help scientists narrow their research inquiries, potentially speeding up the discovery of new […]

IBM and the Georgia Institute of Technology today announced that one of the world’s most powerful supercomputing clusters will anchor Georgia Tech’s new Center for the Study of Systems Biology.

To help usher in a new era of molecular diagnostics and personalized medicine, ASU’s Biodesign Institute and the Translational Genomics Research Institute (TGen) have teamed up to establish the Center for Systems and Computational Biology.

The ubiquitous and usually harmless E. coli bacterium, which has one-seventh the number of genes as a human, has more than 1,000 of them involved in metabolism and metabolic regulation. Activation of random combinations of these genes would theoretically be capable of generating a huge variety of internal states; however, researchers at UCSD will report in the Dec. 27 issue of Proceedings of the National Academy of Sciences (PNAS) that Escherichia coli doesn’t gamble with its metabolism.

Accelerator Corporation, a privately-held biotechnology investment and development company, today announced the formation of Homestead Clinical Corporation, the fourth company in the Accelerator portfolio. The Series A investment in Homestead was led by Accelerator investors MPM Capital, Amgen Ventures, OVP Venture Partners, ARCH Venture Partners, Versant Ventures, and Alexandria Real Estate Equities

The explosion of data from microbial genome sequencing has sparked intense new interest in the field of systems microbiology. Systems microbiology treats microorganisms or microbial communities as a whole, integrating fundamental biological knowledge with genomics and other data to create an integrated picture of how a microbial cell or community operates.