Many people are afflicted with rare illnesses of unknown cause, and finding a common link to such under-studied or “orphaned” diseases as Bardet-Biedl, Alstrom and Meckel-Gruber syndromes can significantly advance the search for causes and treatment. Now, the same Johns Hopkins research team that first identified flaws

Genomatix Software GmbH, a pioneer and leader in the analysis of eukaryotic transcriptional regulation, releases MatBase, a knowledge base of transcription factors (TF).
It contains genomic TF binding sites and protein binding domains, related literature, more than 27.000 known TF – gene interactions, experimentally verified

Researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech have developed a computational model that allows scientists to better understand the metabolism and toxicity of the HIV/AIDS drug zidovudine (azidothymidine, AZT).

The use of computers to advance human disease research – known as bioinformatics — has received a major boost from researchers at the La Jolla Institute for Allergy & Immunology (LIAI), who have used it to successfully predict immune response to one of the most complex viruses known to man

Just because you don’t know much about biology or medicine won’t stop you from helping to someday cure diseases like malaria, HIV, or cancer. In fact, all you need is a computer and an Internet connection and you can play a pivotal role in the search for treatments and cures for some of the world’s [...]

The latest issue of SCIENCE magazine features a brief about the work of UMBI scientists and their Binding Database (BindingDB) project. The BindingDB is a public, web-accessible database of measured binding affinities of small, drug-like molecules for proteins known to be drug-targets. BindingDB supports the discovery of new medications by enhancing the availability and utility [...]

Howard Hughes Medical Institute scientists have developed a new computational approach that integrates data about how genes interact with each other in roundworms, fruit flies and yeast. They hope their database will become a valuable resource for biologists, who might first do a quick online query to learn new clues to how one gene might [...]

KFB - Center of Excellence for Fluorescent Bioanalysis, an authorized Affymetrix Service Provider, and Genomatix Software GmbH signed a cooperation and license agreement that integrates the innovative Genomatix GeneChip Analysis-Pipeline with KFB´s Affymetrix GeneChip Services. These combined services will be made available to the broad KFB customer base in industry and academic institutions.

Johns Hopkins researchers have announced the development of a Web-based, automated computer program that they say greatly simplifies the time-consuming and error-prone process of manually designing artificial pieces of DNA.

IBM and the Georgia Institute of Technology today announced that one of the world’s most powerful supercomputing clusters will anchor Georgia Tech’s new Center for the Study of Systems Biology.