Washington, Apr 24 : A new study has found that men who suffer from migraines may face an increased risk of major cardiovascular disease, especially heart attacks.

Migraines are recurring moderate to severe headaches that may be accompanied by visual disturbances, dizziness, nausea, vomiting or sensitivity to light and sound.

The study was conducted by a team of researchers lead by Tobias Kurth at Harvard Medical School.

As part of the study, researchers studied 20,084 men age 40 to 84 without a previous history of heart disease. From the time they enrolled in the study (between 1981 and 1984) through 2005, the men were sent yearly questionnaires asking about cardiovascular disease events. These included non-fatal ischemic stroke (stroke caused by reduced blood flow to the brain), non-fatal myocardial infarction (heart attack) or death from ischemic cardiovascular disease (an insufficient supply of blood to the heart), coronary revascularization (coronary artery angioplasty or bypass surgery) and angina (chest pain).

Participants were classified as having migraine if they indicated experiencing migraine during the first five years.

Researchers found that a total of 1,449 (7.2 percent) of the men reported migraines, including 434 with frequent. During an average of 15.7 years of follow-up, 2,236 major ischemic cardiovascular disease events occurred, including 750 ischemic strokes, 1,046 myocardial infarctions and 866 ischemic cardiovascular disease deaths, plus 2,257 coronary revascularizations and 2,625 cases of angina.

“Compared with men who did not report migraine, those who reported migraine were at significantly increased risk of major cardiovascular disease and myocardial infarction,” the authors write.

“Several mechanisms have been proposed supporting a biological link between migraine and vascular events. For instance, those with an increased body mass index (BMI) tend to have more frequent and severe migraines as well as an increased risk of heart disease, and it is possible that migraines are a marker for atherosclerosis, or a build-up of plaque in the arteries,” they added.

“However, the increased risk of vascular events remained after controlling for major cardiovascular risk factors in the present data and other studies,” the authors added.

“In conclusion, in this large prospective cohort of apparently healthy middle-aged men, migraine was associated with increased risk of subsequent major cardiovascular disease, which was driven by increased risk of myocardial infarction,” they added.

The findings of the research will be published in the April issue of Archives of Internal Medicine, one of the JAMA/Archives journals. (ANI)